Due to a knee injury, Commanders centre Chase Roullier is expected to miss at least four games.
In Week 3, the Commanders will attempt to get back on track as they visit the fledgling Eagles in a crucial NFC East matchup.
Injured on Sunday's penultimate offensive play for the Commanders after colliding with teammate Sam Cosmi.
Roullier briefly participated in 2022 training camp while still recovering from injuries sustained in 2021.
After the 2020 campaign, secure a four-year, $40.5 million contract extension.